Peritoneal malignant mesothelioma, also known as primary peritoneal mesothelioma, is originated in the peritoneal epithelium and mesothelial cancer organizations. The disease compared with pleural mesothelioma, a rare, slightly higher for men. Benign mesothelioma'll always be single, multi-located in the fallopian tubes, uterus at the top of the peritoneum, other parts of the rare. Malignant mesothelioma is often diffuse, covering all or part of the peritoneum.
Peritoneal mesothelioma originated in the peritoneal epithelium and mesothelial organizations, asbestos dust for the disease-causing substances, may also be caused by certain viruses causes of mesothelioma. Active steps to prevent occupational diseases (such as textiles, construction) is the key to prevention of this disease.
Friday, January 15, 2010
Sunday, January 10, 2010
What are cancer preventive measures?
Do not smoke. There are a variety of cigarette smoke carcinogens such as benzopyrene dimethylnitrosamine, radioactive elements ZIOPO and phenolic compounds, seriously harmful substances are nicotine, carbon monoxide and tar, etc., about 70 lung cancer patients in China % -80% is caused due to long-term smokers.
1, do not smoke. There are a variety of cigarette smoke carcinogens such as benzopyrene dimethylnitrosamine, radioactive elements ZIOPO and phenolic compounds, seriously harmful substances are nicotine, carbon monoxide and tar, etc., about 70 lung cancer patients in China % -80% is caused due to long-term smokers.
2, promoting a scientific diet. Gastrointestinal cancer in China more than 65%, mainly related to water pollution, improper diet or pollution related to dietary fat, protein and carbohydrate structure should be in line with the proportion of health in order to plant food-based, with appropriate vegetables to avoid high-fat, high protein, high-calorie diet, can reduce colorectal cancer, colon cancer, prostate cancer, pancreatic cancer, breast cancer, endometrial cancer, ovarian cancer, and so place.
3, eat moldy and moldy food. Are known to have more than 20 kinds of molds and their toxins have carcinogenic effects in experimental animals, such as aflatoxin B1 are their representatives, our high incidence of esophageal cancer, liver cancer and other income related to the consumption of food contaminated with mold is closely related to.
4, do not drink alcohol or less. Alcohol not only to cirrhosis and liver cancer, but also with the brain, the occurrence of laryngeal cancer, has proven drinking 20-30 grams per day for women suffering from breast cancer more likely than women who never drink 2 times higher.
5, to prevent food contamination. Primarily to prevent the spread of infection or cancer-causing micro-organisms, strict control and monitoring of food additives.
6, to avoid or reduce occupational carcinogen. Because some types of work and workshops with high levels of cancer-causing agent, thus causing a higher incidence of cancer, at present has proved to be kerosene, tar, asphalt, fungi, asbestos, mustard gas, chromium and arsenic, benzene, radioactive substances, together aniline, B-benzene, carbonyl and nickel are carcinogenic, the need to strengthen prevention of occupational diseases.
1, do not smoke. There are a variety of cigarette smoke carcinogens such as benzopyrene dimethylnitrosamine, radioactive elements ZIOPO and phenolic compounds, seriously harmful substances are nicotine, carbon monoxide and tar, etc., about 70 lung cancer patients in China % -80% is caused due to long-term smokers.
2, promoting a scientific diet. Gastrointestinal cancer in China more than 65%, mainly related to water pollution, improper diet or pollution related to dietary fat, protein and carbohydrate structure should be in line with the proportion of health in order to plant food-based, with appropriate vegetables to avoid high-fat, high protein, high-calorie diet, can reduce colorectal cancer, colon cancer, prostate cancer, pancreatic cancer, breast cancer, endometrial cancer, ovarian cancer, and so place.
3, eat moldy and moldy food. Are known to have more than 20 kinds of molds and their toxins have carcinogenic effects in experimental animals, such as aflatoxin B1 are their representatives, our high incidence of esophageal cancer, liver cancer and other income related to the consumption of food contaminated with mold is closely related to.
4, do not drink alcohol or less. Alcohol not only to cirrhosis and liver cancer, but also with the brain, the occurrence of laryngeal cancer, has proven drinking 20-30 grams per day for women suffering from breast cancer more likely than women who never drink 2 times higher.
5, to prevent food contamination. Primarily to prevent the spread of infection or cancer-causing micro-organisms, strict control and monitoring of food additives.
6, to avoid or reduce occupational carcinogen. Because some types of work and workshops with high levels of cancer-causing agent, thus causing a higher incidence of cancer, at present has proved to be kerosene, tar, asphalt, fungi, asbestos, mustard gas, chromium and arsenic, benzene, radioactive substances, together aniline, B-benzene, carbonyl and nickel are carcinogenic, the need to strengthen prevention of occupational diseases.
Thursday, January 7, 2010
Concerned about the children's cancer "three early"
According to medical statistics, 0-14-year-old children, the incidence of malignant tumors accounted for 0.6% of all malignant tumors. Although the incidence is relatively low, but the high degree of malignancy and mortality accounted for 10.7% of child mortality, has become apart from unintentional injuries outside the main cause of child deaths. Children's cancer attributable to their lack of knowledge, the majority of patients with atypical symptoms, children complained of poor, as well as the lack of professional children's cancer doctor and other reasons, in which children can not be the early detection of cancer is often misdiagnosed or even, this is children's cancer patients are not at an early stage to be timely and correct diagnosis and treatment, resulting in an important factor in poor prognosis.
Children's cancer incidence rates according to the order of white blood and central nervous system tumors, malignant lymphoma, a variety of neuroblastoma (common for neuroblastoma, Wilms tumor, hepatoblastoma and retinoblastoma, etc.), abnormal Fetal tumors and rhabdomyosarcoma, osteosarcoma, and so on. They can occur in childhood of all ages, and some malignant tumors such as neuroblastoma may be derived from embryonic period, that is in the neonatal period have been discovered. More than the vast majority of tumors derived from the mother's pregnancy when the embryonic mesoderm of the non-epithelial cells of such tumors in the deeper parts of the body, in addition to the individual tumor outside (such as neuroblastoma specific neural enolase) At present there is no effective screening method of the crowd, it was found more difficult. Although the application of molecular techniques in recent years, there are some reports in the diagnosis, it is still at the research stage and not yet generally used in clinical. Therefore, the diagnosis of malignant tumors in children still rely on parents to detect the disease early leads and specialists in clinical diagnosis.
Parents cope with children are highly vigilant of the following symptoms: (1) systemic performance: longer-term fever, in particular by the short-term antiviral and antibiotic treatment ineffective heat; short-term significant weight loss, weight does not increase or decrease; weakness, Dai Juan; constantly increasing anemia, pale; endocrine disorders, such as asymmetrical such as obesity or precocious puberty. (2) Local performance: mainly local pain, swelling, as well as the surrounding organ mass produce a range of symptoms of oppression. Easier for the early detection of superficial lumps, but in the hidden parts of the body cavity is difficult to lump the early detection of the parents. Parents should note that at this point whether there is tumor compression of adjacent organs produce symptoms, such as mediastinal tumor may cause difficulty in breathing or hold your breath; abdominal gastrointestinal tract tumors often arise because of oppression, nausea, vomiting and intestinal obstruction symptoms; sacral or pelvic tumors can be lead to abnormal bowel movement or urination.
Once the parents found that the above-mentioned abnormal situation, it is timely to set up children's cancer specialist children's cancer hospital physician please check to make a timely diagnosis, so as not to delay treatment. Examination of children's cancer patients, including non-invasive, which means that pairs of children to conduct the inspection without pain, such as the X-ray plain films, B Chao, CT and other tests, more receptive to their families; a-invasive, which means that there is suffering on the children's inspection, such as lumbar puncture, bone marrow puncture, Biopsy examination and other family members are not always easy to accept, but sometimes it is only through these checks in order to obtain the scientific pathology. To make a correct diagnosis of the early development of rational treatment programs to improve treatment and survival rates are very critical. Such as early nephroblastoma (Ⅰ period) more than 90% cure rate, while the transfer time of diagnosis has been late (Ⅳ period) the patient's cure rate is only about 50%. Children's cancer and adult is different from many diseases at an early full access to life-long cure.
Early detection, early diagnosis and early treatment is to improve the efficacy and children's cancer survival rate important aspects. We make the following recommendations to parents: (1) information on the children's cancer of the popular science knowledge, improve the vigilance of the disease, if the conditions for regular medical examinations to children's oncology; (2) careful observation of the child's physical condition, abnormality was found in time to the Please oncology specialist hospitals, doctor checkups for children; (3) Do not believe in non-specialist medical diagnosis; (4) Do not refuse to doctors when necessary, the children engage in invasive examination; (5) Once diagnosed, treatment should be timely and reasonable .
Children's cancer incidence rates according to the order of white blood and central nervous system tumors, malignant lymphoma, a variety of neuroblastoma (common for neuroblastoma, Wilms tumor, hepatoblastoma and retinoblastoma, etc.), abnormal Fetal tumors and rhabdomyosarcoma, osteosarcoma, and so on. They can occur in childhood of all ages, and some malignant tumors such as neuroblastoma may be derived from embryonic period, that is in the neonatal period have been discovered. More than the vast majority of tumors derived from the mother's pregnancy when the embryonic mesoderm of the non-epithelial cells of such tumors in the deeper parts of the body, in addition to the individual tumor outside (such as neuroblastoma specific neural enolase) At present there is no effective screening method of the crowd, it was found more difficult. Although the application of molecular techniques in recent years, there are some reports in the diagnosis, it is still at the research stage and not yet generally used in clinical. Therefore, the diagnosis of malignant tumors in children still rely on parents to detect the disease early leads and specialists in clinical diagnosis.
Parents cope with children are highly vigilant of the following symptoms: (1) systemic performance: longer-term fever, in particular by the short-term antiviral and antibiotic treatment ineffective heat; short-term significant weight loss, weight does not increase or decrease; weakness, Dai Juan; constantly increasing anemia, pale; endocrine disorders, such as asymmetrical such as obesity or precocious puberty. (2) Local performance: mainly local pain, swelling, as well as the surrounding organ mass produce a range of symptoms of oppression. Easier for the early detection of superficial lumps, but in the hidden parts of the body cavity is difficult to lump the early detection of the parents. Parents should note that at this point whether there is tumor compression of adjacent organs produce symptoms, such as mediastinal tumor may cause difficulty in breathing or hold your breath; abdominal gastrointestinal tract tumors often arise because of oppression, nausea, vomiting and intestinal obstruction symptoms; sacral or pelvic tumors can be lead to abnormal bowel movement or urination.
Once the parents found that the above-mentioned abnormal situation, it is timely to set up children's cancer specialist children's cancer hospital physician please check to make a timely diagnosis, so as not to delay treatment. Examination of children's cancer patients, including non-invasive, which means that pairs of children to conduct the inspection without pain, such as the X-ray plain films, B Chao, CT and other tests, more receptive to their families; a-invasive, which means that there is suffering on the children's inspection, such as lumbar puncture, bone marrow puncture, Biopsy examination and other family members are not always easy to accept, but sometimes it is only through these checks in order to obtain the scientific pathology. To make a correct diagnosis of the early development of rational treatment programs to improve treatment and survival rates are very critical. Such as early nephroblastoma (Ⅰ period) more than 90% cure rate, while the transfer time of diagnosis has been late (Ⅳ period) the patient's cure rate is only about 50%. Children's cancer and adult is different from many diseases at an early full access to life-long cure.
Early detection, early diagnosis and early treatment is to improve the efficacy and children's cancer survival rate important aspects. We make the following recommendations to parents: (1) information on the children's cancer of the popular science knowledge, improve the vigilance of the disease, if the conditions for regular medical examinations to children's oncology; (2) careful observation of the child's physical condition, abnormality was found in time to the Please oncology specialist hospitals, doctor checkups for children; (3) Do not believe in non-specialist medical diagnosis; (4) Do not refuse to doctors when necessary, the children engage in invasive examination; (5) Once diagnosed, treatment should be timely and reasonable .
Sunday, January 3, 2010
Clinical staging of peritoneal mesothelioma
Peritoneal mesothelioma (peritoneal mesothelioma) for the primary in the peritoneal epithelium and mesothelial cancer organizations, clinical rare. Can be categorized as pathological adenomatoid mesothelioma (adenomatoid mesothelioma), cystic mesothelioma (cystic mesothelioma) and malignant mesothelioma (peritoneal malignant mesothelioma, PMM).
Peritoneal mesothelioma (peritoneal mesothelioma) for the primary in the peritoneal epithelium and mesothelial cancer organizations, clinical rare. Can be categorized as pathological adenomatoid mesothelioma (adenomatoid mesothelioma), cystic mesothelioma (cystic mesothelioma) and malignant mesothelioma (peritoneal malignant mesothelioma, PMM). The first two are benign. Cystic mesothelioma more common in women, the cause is unknown, occur in the pelvic or accessories around, showing single or multiple cystic masses; patients often palpable abdominal mass due to the treatment. Malignant peritoneal mesothelioma (PMM) account for about 30% of malignant mesothelioma; its occurrence is closely related with exposure to asbestos, about 5% of patients had history of exposure; asbestos fiber intake by mouth, after translocation through the intestinal wall into the peritoneal and pleural metastasis from disease or from. From exposure to asbestos to diagnosis, the disease incubation period of up to 25 to 40 years. But the domestic 1951 ~ 1993 20 reported in the literature 161 cases of PMM in only 1 case had history of exposure to asbestos. ZHOU Ya-kang and other reported 47 cases of mesothelioma there are eight cases of malignant peritoneal mesothelioma, as well as the author collected two cases have history of exposure to asbestos. In the absence of asbestos-exposed populations, its incidence rate is about 1 person / 1 million person-years may be related to certain viral infections and genetic factors. PMM has reported 1 cases of foreign patients come into contact with more than 40 years ago, thorium dioxide colloid (Thorotrast). PMM often occurs in men over the age of 40. Visceral or parietal peritoneum can suffer from; and tumors can be a direct violation of abdominal and pelvic organs; 50% ~ 70% of patients with lymphatic and / or hematogenous metastasis of liver, kidney, adrenal gland, lung, bone and so on.
PMM lack of specific clinical manifestations, may have abdominal pain, constipation, abdominal distention, weight loss, and other intestinal obstruction performance. Physical examination can be found such as ascites or peritoneal mass. Ascites as exudate, in part to bloody. The disease often misdiagnosed as tuberculous peritonitis, recurrent spontaneous peritonitis, mesenteric inflammation or peritoneal metastasis of cancers. Ascites hyaluronic acid were significantly higher than 0.8g / L were found only in PMM. Ascites cytology has a certain value, but the results often hard to tell. Serum carbohydrate antigen -125 (CA125) increased to help diagnose the disease.
Clinical staging: Butchart others will PMM is divided into four: I tumors confined to peritoneal; Ⅱ tumors violation of intra-abdominal lymph nodes; Ⅲ tumors outside the intra-abdominal lymph node metastasis; Ⅳ period of distant metastasis. The classification will help select treatment. PMM has no effective standard treatment. Prognosis is poor, the survival period after diagnosis the median one-year survival of more than 2 years less than 20%. Mainly from cachexia or bowel obstruction, the cause of death is rarely associated with tumor distant metastasis.
Peritoneal mesothelioma (peritoneal mesothelioma) for the primary in the peritoneal epithelium and mesothelial cancer organizations, clinical rare. Can be categorized as pathological adenomatoid mesothelioma (adenomatoid mesothelioma), cystic mesothelioma (cystic mesothelioma) and malignant mesothelioma (peritoneal malignant mesothelioma, PMM). The first two are benign. Cystic mesothelioma more common in women, the cause is unknown, occur in the pelvic or accessories around, showing single or multiple cystic masses; patients often palpable abdominal mass due to the treatment. Malignant peritoneal mesothelioma (PMM) account for about 30% of malignant mesothelioma; its occurrence is closely related with exposure to asbestos, about 5% of patients had history of exposure; asbestos fiber intake by mouth, after translocation through the intestinal wall into the peritoneal and pleural metastasis from disease or from. From exposure to asbestos to diagnosis, the disease incubation period of up to 25 to 40 years. But the domestic 1951 ~ 1993 20 reported in the literature 161 cases of PMM in only 1 case had history of exposure to asbestos. ZHOU Ya-kang and other reported 47 cases of mesothelioma there are eight cases of malignant peritoneal mesothelioma, as well as the author collected two cases have history of exposure to asbestos. In the absence of asbestos-exposed populations, its incidence rate is about 1 person / 1 million person-years may be related to certain viral infections and genetic factors. PMM has reported 1 cases of foreign patients come into contact with more than 40 years ago, thorium dioxide colloid (Thorotrast). PMM often occurs in men over the age of 40. Visceral or parietal peritoneum can suffer from; and tumors can be a direct violation of abdominal and pelvic organs; 50% ~ 70% of patients with lymphatic and / or hematogenous metastasis of liver, kidney, adrenal gland, lung, bone and so on.
PMM lack of specific clinical manifestations, may have abdominal pain, constipation, abdominal distention, weight loss, and other intestinal obstruction performance. Physical examination can be found such as ascites or peritoneal mass. Ascites as exudate, in part to bloody. The disease often misdiagnosed as tuberculous peritonitis, recurrent spontaneous peritonitis, mesenteric inflammation or peritoneal metastasis of cancers. Ascites hyaluronic acid were significantly higher than 0.8g / L were found only in PMM. Ascites cytology has a certain value, but the results often hard to tell. Serum carbohydrate antigen -125 (CA125) increased to help diagnose the disease.
Clinical staging: Butchart others will PMM is divided into four: I tumors confined to peritoneal; Ⅱ tumors violation of intra-abdominal lymph nodes; Ⅲ tumors outside the intra-abdominal lymph node metastasis; Ⅳ period of distant metastasis. The classification will help select treatment. PMM has no effective standard treatment. Prognosis is poor, the survival period after diagnosis the median one-year survival of more than 2 years less than 20%. Mainly from cachexia or bowel obstruction, the cause of death is rarely associated with tumor distant metastasis.
Friday, January 1, 2010
Peritoneal mesothelioma clinical manifestations and diagnosis of
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on.
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on. Peritoneal mesothelioma accounts for about 20% of all mesothelioma cases may occur in 2-92 years, mean age was 54 years, of which about 63% of cases are 45-64 years of age, children are rarely sick.
Clinical
1. Abdominal pain, abdominal distention, ascites, abdominal mass; 2. Anorexia, nausea, vomiting, diarrhea, constipation; 3. Fatigue, fever, weight loss, anemia; 4. Low blood sugar, diffuse abdominal ossification; 5. Combined with other parts, such as peritoneal mesothelioma, mesothelioma, metastasis to other organs and complications of the corresponding performance.
Diagnosis based on
1. Abdominal pain, abdominal distention, ascites, abdominal mass in patients, especially those with asbestos exposure history; 2. Imaging studies have a thin sheet of peritoneal signs and ascites tumor; 3. Ascites cytology; 4. Peritoneal biopsy, laparoscopic and laparotomy and pathological examination can be taken to make the organization confirmed.
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on. Peritoneal mesothelioma accounts for about 20% of all mesothelioma cases may occur in 2-92 years, mean age was 54 years, of which about 63% of cases are 45-64 years of age, children are rarely sick.
Clinical
1. Abdominal pain, abdominal distention, ascites, abdominal mass; 2. Anorexia, nausea, vomiting, diarrhea, constipation; 3. Fatigue, fever, weight loss, anemia; 4. Low blood sugar, diffuse abdominal ossification; 5. Combined with other parts, such as peritoneal mesothelioma, mesothelioma, metastasis to other organs and complications of the corresponding performance.
Diagnosis based on
1. Abdominal pain, abdominal distention, ascites, abdominal mass in patients, especially those with asbestos exposure history; 2. Imaging studies have a thin sheet of peritoneal signs and ascites tumor; 3. Ascites cytology; 4. Peritoneal biopsy, laparoscopic and laparotomy and pathological examination can be taken to make the organization confirmed.
Sunday, December 27, 2009
Examination of peritoneal mesothelioma
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on.
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on. Peritoneal mesothelioma accounts for about 20% of all mesothelioma cases may occur in 2-92 years, mean age was 54 years, of which about 63% of cases are 45-64 years of age, children are rarely sick.
Medical discovery
Abdominal bulging, or showed a frog abdomen, shifting dullness positive; abdominal palpation can reach sizes of single or multiple mass, general tenderness not obvious, such as associated with pleural mesothelioma, may be found positive signs of pleural effusion.
B-ultrasonography and CT examination, a thin sheet can be found tumor images and ascites, ascites exudate, but also to bloody, hyaluronic acid, such as ascites increased to 120ug/ml, helpful in the diagnosis of ascites to find new Biological diagnosis of mesothelioma cells can also be the middle of the ascites skin cell chromosome analysis, assist in diagnosis and laparoscopic peritoneal surface inspection can be seen covered with nodules and plaques, biopsy pathological examination confirm the diagnosis, needs attention and tuberculous peritonitis, peritoneal metastases phase identification.
Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on. Peritoneal mesothelioma accounts for about 20% of all mesothelioma cases may occur in 2-92 years, mean age was 54 years, of which about 63% of cases are 45-64 years of age, children are rarely sick.
Medical discovery
Abdominal bulging, or showed a frog abdomen, shifting dullness positive; abdominal palpation can reach sizes of single or multiple mass, general tenderness not obvious, such as associated with pleural mesothelioma, may be found positive signs of pleural effusion.
B-ultrasonography and CT examination, a thin sheet can be found tumor images and ascites, ascites exudate, but also to bloody, hyaluronic acid, such as ascites increased to 120ug/ml, helpful in the diagnosis of ascites to find new Biological diagnosis of mesothelioma cells can also be the middle of the ascites skin cell chromosome analysis, assist in diagnosis and laparoscopic peritoneal surface inspection can be seen covered with nodules and plaques, biopsy pathological examination confirm the diagnosis, needs attention and tuberculous peritonitis, peritoneal metastases phase identification.
Tuesday, December 22, 2009
A case analysis of the symptoms of peritoneal mesothelioma
Peritoneal mesothelioma originated in the peritoneal epithelium and mesothelial organization whose pathology can be divided into: adenomatoid tumor, cystic mesothelioma, and three kinds of malignant mesothelioma. Peritoneal malignant mesothelioma is a rare malignant tumor, the incidence rate of 1 / 1 million, mostly occurs in middle-aged men and women, incidence of small, its occurrence with exposure to asbestos.
Patients, female, 52 years old, due to "bloating for more than 20 days" on October 21, 2004 into the medicine. Patient for more than 20 days before admission there was no significant incentive to abdominal distention, progressive increase, no fever, night sweats, no abdominal pain, anorexia, no weight loss, no urine, peerless lower extremity edema. Pumping at a local hospital ascites, cancer was not found. Past physical health. Menstruation: 13,7 / 30,48 years of age, color positive, the amount of medium, without dysmenorrhea. Pregnancy history, G2P2L2. Examination: body temperature 36.8 ℃, pulse 84 times / min, breathing 21 times / min, blood pressure 112/80mmHg. Skin and mucosa stained, superficial body lymph nodes are not touched. The normal heart and lung, abdominal bulge, no varicose veins, abdomen soft, no tenderness and rebound tenderness, liver and spleen did not touch, shifting dullness (+). Admission Across gynecological ultrasound examination showed: the uterus and two annexes areas no obvious abnormalities in a large number of ascites. Cancer Series: CA 125> 500u/ml. On October 26, 2004 by Professor gynecological consultations, gynecological examination: development of a normal vulva, vagina smooth, cervix size of the normal, yet smooth. Uterus flat bits, the size of normal activity. After the dome hit small nodules at 1.5cm × 1.0cm. Pairs of non-attachment zone abnormalities, ascites due to some reasons to consider the possibility of Gynecologic Oncology large, in order to confirm the diagnosis, decided to laparoscopic duct exploration, the patient agreed to surgery on October 26, 2004 transferred to gynecology.
Into gynecological after October 28, 2004 in systemic anesthesia laparoscopic duct exploration, intraoperative see the uterus anterior, normal size, bilateral normal-sized ovary, uterus bladder fold milky peritoneal membrane can be seen at large net membrane, intestinal congestion, and other parietal peritoneum. Suck out the yellow ascites 6500ml, in the pelvic parietal peritoneum and the left ovarian biopsy, and membrane-like material will be inspected, the results for the left ovary benign lesions, parietal peritoneum does not rule out malignant mesothelioma, ascites cytology: Cha See cancer (adenocarcinoma). Conditions and their families to talk about tomorrow, is currently not found in patients with intra-abdominal mass in pots and decided to row biopsy and after diagnosis before further treatment. Wash the abdominal cavity, a drainage tube set, a smooth operation, postoperative transfusion and use of antibiotics to prevent infection. Pathological report: malignant peritoneal mesothelioma (The above skin type-based). Immunohistochemistry: MC (+), CK (+), CA125 (-), CA19-9 (-). Postoperative drainage tube patency, a total of 2800ml drain out of ascites, after reviewing routine blood test, liver function, kidney function was normal, after October 18, 2004 ECG monitoring downlink PT regimen, after a smooth, no obvious adverse reaction.
Discussion
Peritoneal mesothelioma originated in the peritoneal epithelium and mesothelial organization whose pathology can be divided into: adenomatoid tumor, cystic mesothelioma, and three kinds of malignant mesothelioma. Peritoneal malignant mesothelioma is a rare malignant tumor, the incidence rate of 1 / 1 million, mostly occurs in middle-aged men and women, incidence of small, its occurrence with exposure to asbestos. It is reported that 60% ~ 80% of patients with asbestos exposure history, a number of cases often without a clear history of asbestos exposure may be related to radiation therapy and chronic peritoneal stimuli. Caused by certain viruses may also cause mesothelioma. Peritoneal mesothelioma clinical manifestations are not specific, the test positive rate is not high, specificity is not strong, clinical diagnosis very difficult. With laparoscopy, ultrasound and CT-guided biopsy technology, as well as pathology, immunohistochemistry and electron microscopy diagnosis of a higher level, more and more cases during his lifetime, or be clearly preoperative pathological diagnosis. Peritoneal mesothelioma should primarily with tuberculous peritonitis, intra-abdominal metastatic carcinoma, other primary in the peritoneum, omentum differentiated from the tumor. To date, peritoneal mesothelioma is still a lack of effects of treatment, the vast majority of scholars, advocates, including surgical resection, postoperative radiotherapy and chemotherapy comprehensive measures. As the case of malignant tumors, where there is unexplained ascites, clinical doctors ruled out ovarian cancer, gastrointestinal cancer of the intra-abdominal metastasis and tuberculosis, peritonitis and other diseases should take into account the possibility of peritoneal malignant mesothelioma should be as soon as possible biopsy or even exploratory laparotomy, a clear diagnosis in order to win treatment time.
Patients, female, 52 years old, due to "bloating for more than 20 days" on October 21, 2004 into the medicine. Patient for more than 20 days before admission there was no significant incentive to abdominal distention, progressive increase, no fever, night sweats, no abdominal pain, anorexia, no weight loss, no urine, peerless lower extremity edema. Pumping at a local hospital ascites, cancer was not found. Past physical health. Menstruation: 13,7 / 30,48 years of age, color positive, the amount of medium, without dysmenorrhea. Pregnancy history, G2P2L2. Examination: body temperature 36.8 ℃, pulse 84 times / min, breathing 21 times / min, blood pressure 112/80mmHg. Skin and mucosa stained, superficial body lymph nodes are not touched. The normal heart and lung, abdominal bulge, no varicose veins, abdomen soft, no tenderness and rebound tenderness, liver and spleen did not touch, shifting dullness (+). Admission Across gynecological ultrasound examination showed: the uterus and two annexes areas no obvious abnormalities in a large number of ascites. Cancer Series: CA 125> 500u/ml. On October 26, 2004 by Professor gynecological consultations, gynecological examination: development of a normal vulva, vagina smooth, cervix size of the normal, yet smooth. Uterus flat bits, the size of normal activity. After the dome hit small nodules at 1.5cm × 1.0cm. Pairs of non-attachment zone abnormalities, ascites due to some reasons to consider the possibility of Gynecologic Oncology large, in order to confirm the diagnosis, decided to laparoscopic duct exploration, the patient agreed to surgery on October 26, 2004 transferred to gynecology.
Into gynecological after October 28, 2004 in systemic anesthesia laparoscopic duct exploration, intraoperative see the uterus anterior, normal size, bilateral normal-sized ovary, uterus bladder fold milky peritoneal membrane can be seen at large net membrane, intestinal congestion, and other parietal peritoneum. Suck out the yellow ascites 6500ml, in the pelvic parietal peritoneum and the left ovarian biopsy, and membrane-like material will be inspected, the results for the left ovary benign lesions, parietal peritoneum does not rule out malignant mesothelioma, ascites cytology: Cha See cancer (adenocarcinoma). Conditions and their families to talk about tomorrow, is currently not found in patients with intra-abdominal mass in pots and decided to row biopsy and after diagnosis before further treatment. Wash the abdominal cavity, a drainage tube set, a smooth operation, postoperative transfusion and use of antibiotics to prevent infection. Pathological report: malignant peritoneal mesothelioma (The above skin type-based). Immunohistochemistry: MC (+), CK (+), CA125 (-), CA19-9 (-). Postoperative drainage tube patency, a total of 2800ml drain out of ascites, after reviewing routine blood test, liver function, kidney function was normal, after October 18, 2004 ECG monitoring downlink PT regimen, after a smooth, no obvious adverse reaction.
Discussion
Peritoneal mesothelioma originated in the peritoneal epithelium and mesothelial organization whose pathology can be divided into: adenomatoid tumor, cystic mesothelioma, and three kinds of malignant mesothelioma. Peritoneal malignant mesothelioma is a rare malignant tumor, the incidence rate of 1 / 1 million, mostly occurs in middle-aged men and women, incidence of small, its occurrence with exposure to asbestos. It is reported that 60% ~ 80% of patients with asbestos exposure history, a number of cases often without a clear history of asbestos exposure may be related to radiation therapy and chronic peritoneal stimuli. Caused by certain viruses may also cause mesothelioma. Peritoneal mesothelioma clinical manifestations are not specific, the test positive rate is not high, specificity is not strong, clinical diagnosis very difficult. With laparoscopy, ultrasound and CT-guided biopsy technology, as well as pathology, immunohistochemistry and electron microscopy diagnosis of a higher level, more and more cases during his lifetime, or be clearly preoperative pathological diagnosis. Peritoneal mesothelioma should primarily with tuberculous peritonitis, intra-abdominal metastatic carcinoma, other primary in the peritoneum, omentum differentiated from the tumor. To date, peritoneal mesothelioma is still a lack of effects of treatment, the vast majority of scholars, advocates, including surgical resection, postoperative radiotherapy and chemotherapy comprehensive measures. As the case of malignant tumors, where there is unexplained ascites, clinical doctors ruled out ovarian cancer, gastrointestinal cancer of the intra-abdominal metastasis and tuberculosis, peritonitis and other diseases should take into account the possibility of peritoneal malignant mesothelioma should be as soon as possible biopsy or even exploratory laparotomy, a clear diagnosis in order to win treatment time.
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