Going into detail in food "tumor factor"

San Francisco VA Medical Center director of Cell Growth Laboratory, U.S. Department of Health under the Department of Veterans Affairs of the Science Advisor, the study's chief scientist, Millie Hughes-Fulford, Dr. said: "The arachidonic acid is the omega-6 family of well-known members. omega-6 fatty acids can open a direct pathway to promote tumor growth. "

The results of this study was published in February of this year's "Cancer Research" on.

University of California, San Francisco for part-time professor at Hughes-Fulford said: "When we put omega-6 fatty acids added to the cell growth medium, we observed that tumor growth rate was double the control."

She further added: "In the study of why the rate of tumor growth so fast, we found that omega-6 can open a number of inflammatory genes, these genes now known to be important cancer-related genes. We continue to ask what to open these genes, eventually found that omega-6 fatty acids can indeed open the named P13 kinase signaling pathway, the enzyme in cancer played an important role. "

Hughes-Fulford believe that this result has important significance, because the modern American's daily diet omega-6 fatty acids, very high quality. omega-6 only existed squeeze the oil of vegetable seeds, such as corn oil, omega-6 fatty acid content was 25 times the health standards, in addition to canola oil, fish and green vegetables all contain omega-6 fatty acids. She also mentioned that in the past 60 years, the United States the incidence of prostate cancer has been growing steadily, which is omega-6 intake increase the same, a fact that diet and prostate cancer suggests a possible link.

The research is based on Fulford and her research team had some of the work, they found that arachidonic acid can stimulate the kind of enzyme known as cPLA-2 generation, and this enzyme would lead to the occurrence of a series of biochemical reaction chain , eventually leading to tumor growth. Mentioned in the previous text of the article, the researchers "along the trace the origin of this biochemical cascade upstream," Hughes-Fulford said: "These fatty acids is to activate signaling pathways, triggering a whole cascade of initiator. "

Hughes-Fulford and her colleagues also found that if they are added to the tumor cell culture of non-steroidal anti-inflammatory factor, or PI3K inhibitor, it will undermine the signaling pathway, these genes will not be opened, tumor growth did not accelerate occur.

Currently, Hughes-Fulford experimental animals to continue her studies, she had her experimental animals take different levels of omega-3 fatty acids and omega-6 fatty acids, observed, "the growth of tumors in animals how well."

Hughes-Fulford said she was a direct impact on the findings of her own daily diet, "I am not a doctor, and can not tell people how to eat is healthy, but I can tell you how to do it myself." She added : "I just eat canola oil and olive oil, we have the right deep-fried foods at arm's length."