Tuesday, December 15, 2009

Peritoneal mesothelioma

Peritoneal mesothelioma is the primary peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on.
Overview of primary peritoneal mesothelioma is peritoneal mesothelial cells in the tumor. Does not have the characteristic clinical manifestations, common signs and symptoms include: abdominal pain, ascites, abdominal distention and abdominal mass and so on. Peritoneal mesothelioma accounts for about 20% of all mesothelioma cases may occur in 2-92 years, mean age was 54 years, of which about 63% of cases are 45-64 years of age, children are rarely sick.

Clinical manifestations 1. Abdominal pain, abdominal distention, ascites, abdominal mass; 2. Anorexia, nausea, vomiting, diarrhea, constipation; 3. Fatigue, fever, weight loss, anemia; 4. Low blood sugar, diffuse abdominal ossification; 5. other parts of the merger, such as mesothelioma, peritoneal mesothelioma, metastasis to other organs and complications of the corresponding performance. Based on a diagnosis. Abdominal pain, abdominal distention, ascites, abdominal mass in patients, especially those with asbestos exposure history; 2. Imaging studies have a thin sheet of peritoneal signs and ascites tumor; 3. Ascites cytology; 4. Peritoneal biopsy, laparoscopy and laparotomy and pathological examination can be taken to make the organization confirmed.

Treatment principles 1. Surgical treatment; 2. Radiotherapy; 3. Chemotherapy; 4. Symptomatic supportive care. The principle of a medication. Combination therapy (such as cis-platinum + cyclophosphamide + vincristine), with intraperitoneal injection of chemotherapy drugs (such as cis-platinum); 2. Intra-abdominal injection of 32P, or colloidal gold, radiotherapy and chemotherapy drugs; 3. surgical cases can not be removed using radiotherapy (60Co) and chemotherapy (cyclophosphamide, vincristine, dactinomycin, etc.). Auxiliary examination 1. Check box limit "A" will help other than confusing the disease; 2. Check box limit "B" will help diagnosis.

Evaluation of a. Cure: remove the tumor without complications, wound healing, clinical symptoms disappeared; 2. Improved: radiotherapy, chemotherapy, symptoms improved after the tumor shrink or slow down the growth rate, appetite improved, weight gain; 3. Unhealed: clinical symptoms and signs do not disappear. Expert Tips peritoneal mesothelioma originated in the peritoneal epithelium and mesothelial organizations, asbestos dust for the disease-causing substances, may also be caused by certain viruses causes of mesothelioma.

Pathology of peritoneal mesothelioma can be divided into: adenomatoid tumor, cystic mesothelioma, and three kinds of malignant mesothelioma. Peritoneal mesothelioma clinical manifestations are not specific, the test positive rate is not high, specificity is not strong, clinical diagnosis very difficult. With laparoscopy, ultrasound and CT-guided biopsy technology, carry out, as well as pathology, immunohistochemistry and electron microscopy diagnosis of a higher level, more and more cases during his lifetime, or be clearly preoperative pathological diagnosis. Peritoneal mesothelioma should primarily with tuberculous peritonitis, intra-abdominal metastatic carcinoma, other primary tumors in the peritoneal omentum phase identification. To date, peritoneal mesothelioma is still a lack of effects of treatment, the vast majority of scholars, advocates, including surgical resection, postoperative radiotherapy and chemotherapy comprehensive treatment measures.

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